{"id":16157,"date":"2026-09-24T21:58:57","date_gmt":"2026-09-24T19:58:57","guid":{"rendered":"https:\/\/everydaybetter.nl\/supplements-for-healthy-aging\/nad-supplements-compared\/"},"modified":"2026-09-24T22:02:33","modified_gmt":"2026-09-24T20:02:33","slug":"nad-supplements-compared","status":"publish","type":"page","link":"https:\/\/everydaybetter.nl\/en\/supplements-for-healthy-aging\/nad-supplements-compared\/","title":{"rendered":"NAD+ supplements compared: NMN, NR, niacin, NADH and NAD+"},"content":{"rendered":"[vc_row type=”in_container” full_screen_row_position=”middle” scene_position=”center” top_padding=”5%” text_color=”dark” text_align=”left” overlay_strength=”0.3″][vc_column column_padding=”no-extra-padding” width=”1\/1″][vc_column_text]\n

NAD+ supplements compared: NMN, NR, niacin, NADH and NAD+<\/h1>\n

Short answer:<\/strong> NMN and NR (nicotinamide riboside) are the best-studied NAD+ boosters: in human studies, 1 gram per day roughly doubles blood NAD+ within about two weeks. Niacin (nicotinic acid) also works well but often causes flushing at higher doses. Nicotinamide raises NAD+ only briefly. For NADH and oral NAD+ there is little evidence that they are absorbed intact. Whatever you choose, pick a product with an independent lab report: testing shows many NAD+ supplements contain less than the label claims.<\/p>\n

NAD+ boosters compared<\/h2>\n\n\n\n\n\n\n\n\n\n\n
Booster<\/th>\nWhat it is<\/th>\nEffect on NAD+ in humans<\/th>\nThings to consider<\/th>\n<\/tr>\n<\/thead>\n
NMN<\/strong> (nicotinamide mononucleotide)<\/td>\nDirect NAD+ precursor<\/td>\nRaises blood NAD+ dose-dependently (250\u20131,000 mg\/day); roughly doubles after 14 days at 1 g\/day<\/td>\nWell tolerated in studies of up to several months; largely converted via gut bacteria<\/td>\n<\/tr>\n
NR<\/strong> (nicotinamide riboside)<\/td>\nVitamin B3 form, precursor of NMN<\/td>\nRaises blood NAD+ similarly to or somewhat more than NMN<\/td>\nWell studied; market testing often finds less than labelled<\/td>\n<\/tr>\n
Niacin<\/strong> (nicotinic acid)<\/td>\nClassic vitamin B3<\/td>\nStrong increase in blood NAD+ in clinical studies<\/td>\nFlushing (redness, warmth, itching) at higher doses; liver strain at high doses<\/td>\n<\/tr>\n
Nicotinamide<\/strong> (niacinamide)<\/td>\nVitamin B3 form<\/td>\nShort, temporary increase (hours)<\/td>\nCheap and well tolerated; effect does not last<\/td>\n<\/tr>\n
NADH<\/strong><\/td>\nReduced form of NAD<\/td>\nLittle evidence that oral NADH is absorbed intact<\/td>\nSmall studies, mostly on fatigue; low quality of evidence<\/td>\n<\/tr>\n
NAD+ (oral)<\/strong><\/td>\nThe end product itself<\/td>\nLargely broken down in the gut into smaller precursors<\/td>\nIn testing, many products contained hardly any NAD+<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

NMN vs NR: what do head-to-head studies show?<\/h2>\n