Buying TMG in the Netherlands, Belgium, and Europe: what should you look for?
Buying TMG in the Netherlands, Belgium, or elsewhere in Europe? TMG (trimethylglycine, also called betaine) is widely available from suppliers shipping from the Netherlands or the EU. When choosing, pay particular attention to the dosage per capsule (500 mg is common), independent purity tests, and whether the price includes VAT, without surprise costs afterwards.
On this page, you will read exactly what TMG is, why it is often used together with NMN, what you should specifically look for in a provider delivering to the Netherlands, Belgium, and the rest of Europe, and what a fair price-quality ratio means for this type of supplement. We stick to what research and official sources actually show — without exaggerated promises.
What is TMG and what is it used for?
TMG stands for trimethylglycine, naturally also known as betaine. It is a substance with three methyl groups that the body can use as a methyl group donor within methylation processes. One of the best-known pathways in this regard is the BHMT pathway (betaine-homocysteine methyltransferase): TMG transfers a methyl group to convert homocysteine into methionine. Methionine, in turn, is a building block for SAMe (S-adenosylmethionine), the most important methyl group donor in the body.
Why is this relevant for daily practice? Methylation plays a role in a wide range of bodily processes, from the production of neurotransmitters to the regulation of homocysteine levels. Elevated homocysteine levels are associated in literature with cardiovascular risk factors, which explains why betaine supplementation has been a subject of research for decades. Clinical research shows that low doses of betaine can lower plasma homocysteine levels in both the short and long term in healthy adults. See the studies “Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women” and “The effect of low doses of betaine on plasma homocysteine in healthy volunteers”, both published via PubMed.
Betaine (TMG) is also registered as a recognized nutrient in the Dietary Supplement Label Database of the NIH Office of Dietary Supplements.
Would you like the full background, including the role of B vitamins and commonly used terminology? Read our comprehensive explanation at What is TMG and how does TMG work?, view the TMG research, or go directly to how much TMG you need per day.
TMG and NMN: why are they often used together?
Anyone delving into NMN supplementation quickly encounters the term “methylation load.” The underlying thought: nicotinamide, a breakdown product of NAD+ metabolism, is methylated in the body by the enzyme nicotinamide N-methyltransferase (NNMT) into methylnicotinamide. This process consumes methyl groups that the body also needs for other methylation processes. This is one of the reasons why TMG is often mentioned within the longevity community as a supplement alongside NMN — as an extra methyl group donor in addition to what the body already produces itself.
It is important to be honest about what we do and do not know for certain: NNMT and the role of methylation in aging are an active field of research (see, for example, this overview on NNMT as a therapeutic area of focus in aging, published via PubMed Central), but there is no conclusive evidence that TMG supplementation provides a measurable benefit for healthy users of NMN.
It is a biochemically plausible, commonly used combination — not a proven requirement. If you use NMN and are considering adding TMG, it is a reasonable, well-founded choice, but not a necessity.
Buying TMG in the Netherlands, Belgium, or Europe: what to look for
Dosage per capsule. In the Dutch and European market, 500 mg per capsule is the most common dosage, often with a recommended intake of one to three capsules per day (i.e., 500–1,500 mg total). Check whether the dosage on the label corresponds to what has been used in research — the two PubMed studies mentioned above worked with relatively low dosages, and higher dosages are not necessarily better.
Independent purity test. Ask yourself whether a provider makes a certificate of analysis (CoA) from an external, independent laboratory available. This proves that the product actually contains what is stated on the label, free from contaminants. At Every Day Better, the same independent testing practice applies to TMG as to NMN — see our NMN certificates as an example.
Form: capsules or powder. Capsules are easier to dose and more convenient on the go; powder is often more flexible in dosage and cheaper per gram, but requires a scale or measuring spoon for accurate intake. If you are unsure whether TMG and regular betaine are the same, or which form suits your situation, read TMG vs. betaine.
Shipping to the Netherlands, Belgium, or the rest of Europe, and price. Does the supplier ship from the Netherlands or the EU, or does your order have to pass through customs? For orders from outside the EU, import duties, VAT additional assessments, and longer delivery times may come into play — exactly the same considerations that apply to buying NMN without foreign shipping costs. Also check if the price shown actually includes VAT; our full shipping policy shows the exact rates and delivery times per region.
Possible side effects and caution. TMG is generally well tolerated, but as with any supplement, mild side effects can occur, particularly at higher dosages. Are you using medication, are you pregnant or breastfeeding, or do you have a medical condition? Always consult a physician first — a supplement is not a substitute for medical treatment. Read the full explanation at TMG side effects.
Regulations in the Netherlands, Belgium, and the EU. Betaine (TMG) has been assessed as a novel food under Regulation (EU) 2015/2283, with a positive safety assessment by the EFSA. In the Netherlands, supervision of dietary supplements falls under the NVWA; in Belgium under the FAMHP and the FPS Public Health. In practical terms, this means: a TMG supplement that is legally sold in the Netherlands may also be legally sold and used in Belgium and the rest of the EU.
How Every Day Better fulfills this
Buying TMG in the Netherlands, Belgium, or Europe is done at Every Day Better in one simple order. Our TMG Capsules (60x500mg) are formulated with a dosage that aligns with what is common in research, and independently tested for purity — the same approach we use for NMN. Orders are shipped from the Netherlands: no customs within the EU, the price you see is always inclusive of VAT, and shipping costs are fixed and transparent — €4.90 (Netherlands and Belgium) or €6.90 (rest of Europe) for orders under €50, and free from €50.
Do you use NMN and TMG together? Then the NMN & TMG bundle is often the most economical option.
Every Day Better vs. a typical TMG provider
The comparison below is intentionally qualitative: we do not mention competitor prices here, as these vary greatly per provider and per moment — supplement this yourself if you wish to show concrete prices.
| Every Day Better | Typical provider | |
|---|---|---|
| Dosage | 500 mg per capsule | Varies (250–1,000 mg), not always clear on the packaging |
| Purity test | Independently tested, certificate available | Not always made public |
| Shipping | From the Netherlands/EU | Varies — always check this in advance |
| Price transparency | Final price = payment price, incl. VAT | Not always shown incl. VAT |
| Combination options | NMN & TMG bundle available | Individual products, rarely combined |
The most important question this table answers is not “who is cheapest,” but “where do I know exactly what I am buying”: dosage, purity, and the final price without surprises carry more weight than the lowest advertised price.
Frequently Asked Questions
How much TMG (betaine) should I take per day? The common dosage in available research and in the Dutch/European supplement range is between 500 mg and 1,500 mg per day. See our comprehensive dosage guide for details and titration.
Are there side effects with TMG? TMG is generally well tolerated. Read which side effects are reported and at which dosage they occur more frequently.
Can I combine TMG with NMN? Yes, TMG and NMN work through different mechanisms and are often used together within the longevity community, partly due to the role of TMG as a methyl group donor. View the NMN & TMG bundle.
Is TMG the same as betaine? Yes, TMG (trimethylglycine) and betaine are two names for the same substance. You will encounter both terms on labels. Read more about the nuances at TMG vs. betaine.
Why do people take TMG alongside B vitamins? B vitamins such as folic acid (B9) and vitamin B12 also play a role in methylation, via a different pathway than TMG. Therefore, they are sometimes combined within a supplement routine, although this is not a requirement.
Where can I see if a TMG supplement has been independently tested? Ask for a certificate of analysis (CoA) from an external laboratory — the same independent testing practice that we employ for our NMN certificates.
Do you ship TMG to the Netherlands, Belgium, and the rest of Europe? Yes. Buying TMG in the Netherlands, Belgium, or the rest of Europe is always possible at Every Day Better — we ship from the Netherlands, without customs within the EU. See our shipping policy for exact rates and delivery times per country.
Is TMG (betaine) legally available throughout Europe? Yes. Buying TMG in the Netherlands, Belgium, or elsewhere in Europe is legal — betaine has been assessed in the EU as a novel food under Regulation (EU) 2015/2283, with a positive safety assessment by the EFSA. Consequently, it may be sold and used as a dietary supplement EU-wide, including in the Netherlands and Belgium.
Can I stop taking TMG without any problems? TMG does not build physical dependence; you can stop in consultation with your physician or at your own discretion. If you notice unexpected symptoms, please contact a physician.
In summary
Buying TMG in the Netherlands, Belgium, or Europe is widely and legally possible. TMG supplementation is scientifically well-documented in the field of homocysteine reduction, and relatively easy to assess for quality: pay attention to dosage, an independent certificate, the shipping location, and whether the price includes VAT. An absolute miracle-cure claim does not belong there — rather a sober, well-founded choice that fits what research has shown so far. Are you considering buying TMG in the Netherlands, Belgium, or Europe yourself? Then view our TMG Capsules (60x500mg).
