NMN supplements

What is NMN and what does it do?

NMN (nicotinamide mononucleotide) is a nucleotide that occurs naturally in the body and in small amounts in foods such as broccoli, edamame and avocado. Inside the cell, NMN is converted into NAD⁺ (nicotinamide adenine dinucleotide) in a single step. NAD⁺ is a coenzyme needed for energy metabolism in the mitochondria and for enzymes involved in DNA maintenance, such as sirtuins and PARPs.

Research shows that NAD⁺ levels in various tissues decline as we age. Human studies show that daily NMN intake raises NAD⁺ concentrations in the blood, for example at doses of 300 to 900 mg per day for 60 days (Yi et al., GeroScience, 2023). What this means for healthy ageing in the long term is still being studied. Read more in how NMN works and in our overview of the latest NMN studies.

NMN capsules or NMN powder: which suits you?

	NMN capsules	NMN powder
Dosage	Fixed: 250 mg per capsule	Flexible with measuring scoop
How to take	Swallow with water, also on the go	Under the tongue or dissolved in water or yoghurt
Price per 250 mg	€0.74 to €0.85	€0.45
Best for	Beginners and anyone who wants a fixed routine	Experienced users and higher doses

Both forms contain the same raw material with the same test reports. See all variants under NMN capsules 250 mg and NMN powder, or read how to take NMN powder.

How much NMN per day?

Human studies have investigated doses between 250 mg and 1,250 mg per day. Most people start with 250 to 500 mg per day (1 to 2 capsules), preferably in the morning. A study using 1,250 mg per day for 4 weeks found no serious side effects in healthy adults (Fukamizu et al., Scientific Reports, 2022). More explanation and a calculation per pack can be found under NMN dosage and NMN side effects.

How long does a pack last?

• 60 capsules: 60 days at 250 mg per day, 30 days at 500 mg per day.
• 120 capsules: 120 days at 250 mg per day, 60 days at 500 mg per day.
• 30 g powder: 120 days at 250 mg per day, 60 days at 500 mg per day.

Combining NMN with TMG or GlyNAC

Many users combine NMN with TMG (trimethylglycine). The idea behind it: breaking down the nicotinamide part of NAD⁺ uses up methyl groups, and TMG is a methyl group donor. This is a theoretical rationale; controlled studies of the combination are still lacking. Another combination is NMN with GlyNAC, which targets glutathione. Read more in NMN, TMG and GlyNAC as a longevity stack.

NMN vs NR

NR (nicotinamide riboside) is another NAD⁺ precursor. In the cell, NR is first converted into NMN and then into NAD⁺, so NMN is one step closer to NAD⁺. Both raise blood NAD⁺ levels in studies. Read an in-depth comparison in NMN vs NR.

What to look for when buying NMN

• An independent test report for every batch covering purity (HPLC) and checks for heavy metals and microbiology. Our reports are on NMN certificates.
• Form of NMN: β-NMN is the biologically active form.
• A clear dose per capsule or per scoop.
• No unnecessary fillers or artificial additives.
• Price per 250 mg rather than price per jar, so you compare fairly.

Want to compare brands? See choosing the best NMN supplement or go straight to buying NMN at Every Day Better.

Frequently asked questions about NMN supplements

Find more answers in questions about NMN. Food supplements are not a substitute for a varied diet and a healthy lifestyle. Consult a doctor if you are pregnant, breastfeeding, taking medication or have medical complaints.